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Activation of p115-RhoGEF Requires Direct Association of Gα(13) and the Dbl Homology Domain
RGS-containing RhoGEFs (RGS-RhoGEFs) represent a direct link between the G(12) class of heterotrimeric G proteins and the monomeric GTPases. In addition to the canonical Dbl homology (DH) and pleckstrin homology domains that carry out the guanine nucleotide exchange factor (GEF) activity toward RhoA...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408165/ https://ncbi.nlm.nih.gov/pubmed/22661716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.333716 |
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