Identification of Critical Residues in Gα(13) for Stimulation of p115RhoGEF Activity and the Structure of the Gα(13)-p115RhoGEF Regulator of G Protein Signaling Homology (RH) Domain Complex

RH-RhoGEFs are a family of guanine nucleotide exchange factors that contain a regulator of G protein signaling homology (RH) domain. The heterotrimeric G protein Gα(13) stimulates the guanine nucleotide exchange factor (GEF) activity of RH-RhoGEFs, leading to activation of RhoA. The mechanism by whi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hajicek, Nicole, Kukimoto-Niino, Mutsuko, Mishima-Tsumagari, Chiemi, Chow, Christina R., Shirouzu, Mikako, Terada, Takaho, Patel, Maulik, Yokoyama, Shigeyuki, Kozasa, Tohru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121507/
https://ncbi.nlm.nih.gov/pubmed/21507947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.201392
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados