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Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase

The Pleckstrin homology (PH) domains from the Lbc family of Rho Guanine Nucleotide Exchange Factors (Lbc RhoGEFs) interact with activated Rho family GTPases. All 7 Lbc RhoGEFs associate directly with activated Rho GTPases via their PH domains. However, the binding affinities between the PH domains a...

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Detalhes bibliográficos
Publicado no:Data Brief
Main Authors: Chen, Zhe, Gutowski, Steven, Sternweis, Paul C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988292/
https://ncbi.nlm.nih.gov/pubmed/29876405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dib.2018.01.024
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