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Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase

The Pleckstrin homology (PH) domains from the Lbc family of Rho Guanine Nucleotide Exchange Factors (Lbc RhoGEFs) interact with activated Rho family GTPases. All 7 Lbc RhoGEFs associate directly with activated Rho GTPases via their PH domains. However, the binding affinities between the PH domains a...

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Bibliografische gegevens
Gepubliceerd in:Data Brief
Hoofdauteurs: Chen, Zhe, Gutowski, Steven, Sternweis, Paul C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988292/
https://ncbi.nlm.nih.gov/pubmed/29876405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dib.2018.01.024
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