Direct Regulation of p190RhoGEF by Activated Rho and Rac GTPases

Rho family GTPases regulate a wide range of cellular processes. This includes cellular dynamics where three subfamilies, Rho, Rac, and Cdc42, are known to regulate cell shape and migration though coordinate action. Activation of Rho proteins largely depends on Rho Guanine nucleotide Exchange Factors...

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Veröffentlicht in:J Struct Biol
Hauptverfasser: Dada, Olugbenga, Gutowski, Stephen, Brautigam, Chad A., Chen, Zhe, Sternweis, Paul C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835413/
https://ncbi.nlm.nih.gov/pubmed/29196061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2017.11.014
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