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Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase

The Pleckstrin homology (PH) domains from the Lbc family of Rho Guanine Nucleotide Exchange Factors (Lbc RhoGEFs) interact with activated Rho family GTPases. All 7 Lbc RhoGEFs associate directly with activated Rho GTPases via their PH domains. However, the binding affinities between the PH domains a...

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Enregistré dans:
Détails bibliographiques
Publié dans:Data Brief
Auteurs principaux: Chen, Zhe, Gutowski, Steven, Sternweis, Paul C.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988292/
https://ncbi.nlm.nih.gov/pubmed/29876405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dib.2018.01.024
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