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Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase

The Pleckstrin homology (PH) domains from the Lbc family of Rho Guanine Nucleotide Exchange Factors (Lbc RhoGEFs) interact with activated Rho family GTPases. All 7 Lbc RhoGEFs associate directly with activated Rho GTPases via their PH domains. However, the binding affinities between the PH domains a...

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Detaylı Bibliyografya
Yayımlandı:Data Brief
Asıl Yazarlar: Chen, Zhe, Gutowski, Steven, Sternweis, Paul C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988292/
https://ncbi.nlm.nih.gov/pubmed/29876405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dib.2018.01.024
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