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Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase

The Pleckstrin homology (PH) domains from the Lbc family of Rho Guanine Nucleotide Exchange Factors (Lbc RhoGEFs) interact with activated Rho family GTPases. All 7 Lbc RhoGEFs associate directly with activated Rho GTPases via their PH domains. However, the binding affinities between the PH domains a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Data Brief
Prif Awduron: Chen, Zhe, Gutowski, Steven, Sternweis, Paul C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988292/
https://ncbi.nlm.nih.gov/pubmed/29876405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dib.2018.01.024
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