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Gα12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF
Heterotrimeric G proteins, G12 and G13, have been shown to transduce signals from G protein-coupled receptors to activate Rho GTPase in cells. Recently, we identified p115RhoGEF, one of the guanine nucleotide exchange factors (GEFs) for Rho, as a direct link between Gα13 and Rho [Kozasa, T., et al....
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141065/ https://ncbi.nlm.nih.gov/pubmed/12515866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0234057100 |
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