Gα12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF
Heterotrimeric G proteins, G12 and G13, have been shown to transduce signals from G protein-coupled receptors to activate Rho GTPase in cells. Recently, we identified p115RhoGEF, one of the guanine nucleotide exchange factors (GEFs) for Rho, as a direct link between Gα13 and Rho [Kozasa, T., et al....
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141065/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12515866/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0234057100 |
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