RhoGEF Ect2 supports RhoA activity at cell–cell junctions through desmoplakin
We describe a mechanism by which the desmosome component, desmoplakin, can recruit and control the activity of the contractile signaling regulator RhoA at cardiomyocyte and keratinocyte intercellular junctions, with implications for cardiocutaneous health and disease pathogenesis. Desmoplakin (DP) i...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Life Science Alliance LLC
2026-06-01
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| Serie: | Life Science Alliance |
| Accesso online: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202503454 |
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