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Roles of the Dbl family of RhoGEFs in mechanotransduction – a review

Rho guanine nucleotide exchange factors (RhoGEFs) comprise a wide range of proteins with a common domain responsible for the activation of the Rho family of small GTPases and various domains in other regions. The evolutionary divergence of RhoGEFs enables actin cytoskeletal reorganization, leading t...

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Autors principals: Kazumasa Ohashi, Aoi Kunitomi, Shuhei Chiba, Kensaku Mizuno
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2024-10-01
Col·lecció:Frontiers in Cell and Developmental Biology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fcell.2024.1485725/full
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