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The RGS-RhoGEFs control the amplitude of YAP1 activation by serum
Actin-dependent mechanisms drive the nuclear translocation of Yap1 to enable its co-activation of transcription factors that induce pro-growth and survival programs. While Rho GTPases are necessary for the nuclear import of YAP1, the relevant Guanine Exchange Factors (GEFs) and GTPase Activating Pro...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7841162/ https://ncbi.nlm.nih.gov/pubmed/33504879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82027-4 |
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