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The Gα12-RGS RhoGEF-RhoA signalling pathway regulates neurotransmitter release in C. elegans
In Caenorhabditis elegans adults, the single Rho GTPase orthologue, RHO-1, stimulates neurotransmitter release at synapses. We show that one of the pathways acting upstream of RHO-1 in acetylcholine (ACh)-releasing motor neurons depends on Gα12 (GPA-12), which acts via the single C. elegans RGS RhoG...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698903/ https://ncbi.nlm.nih.gov/pubmed/17139250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601458 |
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