PYK2/PDZ-RhoGEF links Ca(2+) signaling to RhoA

OBJECTIVE: Ras homolog gene family member A (RhoA)/Rho-kinase-mediated Ca(2+) sensitization is a critical component of constrictor responses. The present study investigates how angiotensin II activates RhoA. METHODS AND RESULTS: Adenoviral vectors were used to manipulate the expression of regulator...

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Bibliographic Details
Main Authors: Ying, Zhekang, Giachini, Fernanda R.C., Tostes, Rita C., Webb, R. Clinton
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939713/
https://ncbi.nlm.nih.gov/pubmed/19759375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.190892
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