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Salicylates dilate blood vessels through inhibiting PYK2-mediated RhoA/Rho-kinase activation

AIMS: Compared with other non-steroid anti-inflammatory drugs (NSAIDs), aspirin is not correlated to hypertension. It has been shown that aspirin has unique vasodilator action in vivo, offering an explanation for the unique blood pressure effect of aspirin. In the present study, we investigate the m...

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Detalhes bibliográficos
Main Authors: Ying, Zhekang, Giachini, Fernanda R.C., Tostes, Rita C., Webb, Robert Clinton
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695702/
https://ncbi.nlm.nih.gov/pubmed/19276129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp084
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