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Salicylates dilate blood vessels through inhibiting PYK2-mediated RhoA/Rho-kinase activation

AIMS: Compared with other non-steroid anti-inflammatory drugs (NSAIDs), aspirin is not correlated to hypertension. It has been shown that aspirin has unique vasodilator action in vivo, offering an explanation for the unique blood pressure effect of aspirin. In the present study, we investigate the m...

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Hlavní autoři: Ying, Zhekang, Giachini, Fernanda R.C., Tostes, Rita C., Webb, Robert Clinton
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695702/
https://ncbi.nlm.nih.gov/pubmed/19276129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp084
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