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RhoA/Rho-kinase and vascular diseases: what is the link?
RhoA/Rho-kinase pathway plays an important role in many pathological conditions. RhoA participates in the regulation of smooth muscle tone and activates many downstream kinases. The best characterized are the serine/threonine kinase isoforms (Rho-kinase or ROCK), ROCKα/ROCK2 and ROCKβ/ROCK1. ROCK is...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996825/ https://ncbi.nlm.nih.gov/pubmed/20668910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0460-1 |
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