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Salicylates dilate blood vessels through inhibiting PYK2-mediated RhoA/Rho-kinase activation

AIMS: Compared with other non-steroid anti-inflammatory drugs (NSAIDs), aspirin is not correlated to hypertension. It has been shown that aspirin has unique vasodilator action in vivo, offering an explanation for the unique blood pressure effect of aspirin. In the present study, we investigate the m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ying, Zhekang, Giachini, Fernanda R.C., Tostes, Rita C., Webb, Robert Clinton
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695702/
https://ncbi.nlm.nih.gov/pubmed/19276129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp084
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