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Salicylates dilate blood vessels through inhibiting PYK2-mediated RhoA/Rho-kinase activation

AIMS: Compared with other non-steroid anti-inflammatory drugs (NSAIDs), aspirin is not correlated to hypertension. It has been shown that aspirin has unique vasodilator action in vivo, offering an explanation for the unique blood pressure effect of aspirin. In the present study, we investigate the m...

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Détails bibliographiques
Auteurs principaux: Ying, Zhekang, Giachini, Fernanda R.C., Tostes, Rita C., Webb, Robert Clinton
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695702/
https://ncbi.nlm.nih.gov/pubmed/19276129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp084
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