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Salicylates dilate blood vessels through inhibiting PYK2-mediated RhoA/Rho-kinase activation

AIMS: Compared with other non-steroid anti-inflammatory drugs (NSAIDs), aspirin is not correlated to hypertension. It has been shown that aspirin has unique vasodilator action in vivo, offering an explanation for the unique blood pressure effect of aspirin. In the present study, we investigate the m...

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Библиографические подробности
Главные авторы: Ying, Zhekang, Giachini, Fernanda R.C., Tostes, Rita C., Webb, Robert Clinton
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695702/
https://ncbi.nlm.nih.gov/pubmed/19276129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp084
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