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Up-Regulation of the RhoA/Rho-Kinase Signaling Pathway in Corpus Cavernosum from Endothelial Nitric-Oxide Synthase (NOS), but Not Neuronal NOS, Null Mice

We tested the hypothesis that the basal release of nitric oxide (NO) from endothelial cells modulates contractile activity in the corpus cavernosum (CC) via inhibition of the RhoA/Rho-kinase signaling pathway. Cavernosal strips from wild-type (WT), endothelial nitric-oxide synthase knockout [eNOS(−/...

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Autori principali: Priviero, Fernanda B. M., Jin, Li-Ming, Ying, Zhekang, Teixeira, Cleber E., Webb, R. Clinton
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846021/
https://ncbi.nlm.nih.gov/pubmed/20093396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.160606
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