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PDZ-RhoGEF is essential for CXCR4-driven breast tumor cell motility through spatial regulation of RhoA
The CXCL12–CXCR4 chemokine signaling pathway is a well-established driver of cancer progression. One key process promoted by CXCR4 stimulation is tumor cell motility; however, the specific signaling pathways leading to migration remain poorly understood. Previously, we have shown that CXCL12 stimula...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784824/ https://ncbi.nlm.nih.gov/pubmed/23868972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.132381 |
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