PDZ-RhoGEF is essential for CXCR4-driven breast tumor cell motility through spatial regulation of RhoA

The CXCL12–CXCR4 chemokine signaling pathway is a well-established driver of cancer progression. One key process promoted by CXCR4 stimulation is tumor cell motility; however, the specific signaling pathways leading to migration remain poorly understood. Previously, we have shown that CXCL12 stimula...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Struckhoff, Amanda P., Rana, Manish K., Kher, Swapnil S., Burow, Matt E., Hagan, Joseph L., Del Valle, Luis, Worthylake, Rebecca A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784824/
https://ncbi.nlm.nih.gov/pubmed/23868972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.132381
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk