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Activation of nuclear factor-κB is necessary for myotrophin-induced cardiac hypertrophy

The transcription factor nuclear factor-κB (NF-κB) regulates expression of a variety of genes involved in immune responses, inflammation, proliferation, and programmed cell death (apoptosis). Here, we show that in rat neonatal ventricular cardiomyocytes, activation of NF-κB is involved in the hypert...

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Bibliographic Details
Main Authors: Gupta, Sudhiranjan, Purcell, Nicole H., Lin, Anning, Sen, Subha
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173971/
https://ncbi.nlm.nih.gov/pubmed/12486112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200207149
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