Nuclear Co-translocation of Myotrophin and p65 Stimulates Myocyte Growth: REGULATION BY MYOTROPHIN HAIRPIN LOOPS

Myotrophin, a 12-kDa ankyrin repeat protein, stimulates protein synthesis and cardiomyocyte growth to initiate cardiac hypertrophy by activating the NF-κB signaling cascade. We found that, after internalization into myocytes, myotrophin cotranslocates into the nucleus with p65 to stimulate myocyte g...

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Hlavní autoři: Das, Biswajit, Gupta, Sudhiranjan, Vasanji, Amit, Xu, Zhen, Misra, Saurav, Sen, Subha
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Molecular Basis of Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562064/
https://ncbi.nlm.nih.gov/pubmed/18693253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801210200
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