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Influence of p53 in the transition of myotrophin-induced cardiac hypertrophy to heart failure
AIMS: Cardiac-specific overexpression of myotrophin (myo) protein in transgenic (myo-Tg) mice results in hypertrophy at 4 weeks that progresses to heart failure (HF) by 36 weeks. Gene profiling showed that p53 expression increases as hypertrophy worsens to HF, suggesting that p53 may influence myo-i...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904660/ https://ncbi.nlm.nih.gov/pubmed/20202977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq068 |
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