Silencing the myotrophin gene by RNA interference leads to the regression of cardiac hypertrophy

Myotrophin-induced activation of NF-κB has been shown to be associated with cardiac hypertrophy (CH) that progresses to heart failure (HF). In the present study, we examined the cause-and-effect relationship between myotrophin and NF-κB activation using small hairpin RNA (shRNA) against myotrophin b...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gupta, Sudhiranjan, Maitra, Ratan, Young, Dave, Gupta, Anasuya, Sen, Subha
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2009
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724203/
https://ncbi.nlm.nih.gov/pubmed/19502558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00294.2009
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