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Silencing the myotrophin gene by RNA interference leads to the regression of cardiac hypertrophy
Myotrophin-induced activation of NF-κB has been shown to be associated with cardiac hypertrophy (CH) that progresses to heart failure (HF). In the present study, we examined the cause-and-effect relationship between myotrophin and NF-κB activation using small hairpin RNA (shRNA) against myotrophin b...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Physiological Society
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724203/ https://ncbi.nlm.nih.gov/pubmed/19502558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00294.2009 |
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