RhoA protects the mouse heart against ischemia/reperfusion injury

The small GTPase RhoA serves as a nodal point for signaling through hormones and mechanical stretch. However, the role of RhoA signaling in cardiac pathophysiology is poorly understood. To address this issue, we generated mice with cardiomyocyte-specific conditional expression of low levels of activ...

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Hlavní autoři: Xiang, Sunny Yang, Vanhoutte, Davy, Del Re, Dominic P., Purcell, Nicole H., Ling, Haiyun, Banerjee, Indroneal, Bossuyt, Julie, Lang, Richard A., Zheng, Yi, Matkovich, Scot J., Miyamoto, Shigeki, Molkentin, Jeffery D., Dorn, Gerald W., Brown, Joan Heller
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148727/
https://ncbi.nlm.nih.gov/pubmed/21747165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44371
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