RhoA protects the mouse heart against ischemia/reperfusion injury

The small GTPase RhoA serves as a nodal point for signaling through hormones and mechanical stretch. However, the role of RhoA signaling in cardiac pathophysiology is poorly understood. To address this issue, we generated mice with cardiomyocyte-specific conditional expression of low levels of activ...

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Detalhes bibliográficos
Main Authors: Xiang, Sunny Yang, Vanhoutte, Davy, Del Re, Dominic P., Purcell, Nicole H., Ling, Haiyun, Banerjee, Indroneal, Bossuyt, Julie, Lang, Richard A., Zheng, Yi, Matkovich, Scot J., Miyamoto, Shigeki, Molkentin, Jeffery D., Dorn, Gerald W., Brown, Joan Heller
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148727/
https://ncbi.nlm.nih.gov/pubmed/21747165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44371
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