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RhoA regulates Drp1 mediated mitochondrial fission through ROCK to protect cardiomyocytes
Cardiac ischemia/reperfusion, loss of blood flow and its subsequent restoration, causes damage to the heart. Oxidative stress from ischemia/reperfusion leads to dysfunction and death of cardiomyocytes, increasing the risk of progression to heart failure. Alterations in mitochondrial dynamics, in par...
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| Vydáno v: | Cell Signal |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6361616/ https://ncbi.nlm.nih.gov/pubmed/29953931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.06.012 |
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