RhoA protects the mouse heart against ischemia/reperfusion injury

The small GTPase RhoA serves as a nodal point for signaling through hormones and mechanical stretch. However, the role of RhoA signaling in cardiac pathophysiology is poorly understood. To address this issue, we generated mice with cardiomyocyte-specific conditional expression of low levels of activ...

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Autors principals: Xiang, Sunny Yang, Vanhoutte, Davy, Del Re, Dominic P., Purcell, Nicole H., Ling, Haiyun, Banerjee, Indroneal, Bossuyt, Julie, Lang, Richard A., Zheng, Yi, Matkovich, Scot J., Miyamoto, Shigeki, Molkentin, Jeffery D., Dorn, Gerald W., Brown, Joan Heller
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148727/
https://ncbi.nlm.nih.gov/pubmed/21747165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44371
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