Selective Coupling of the S1P(3) Receptor Subtype to S1P-mediated RhoA Activation and Cardioprotection

Sphingosine-1-phosphate (S1P), a bioactive lysophospholipid, is generated and released at sites of tissue injury in the heart and can act on S1P(1), S1P(2), and S1P(3) receptor subtypes to affect cardiovascular responses. We established that S1P causes little phosphoinositide hydrolysis and does not...

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Veröffentlicht in:J Mol Cell Cardiol
Hauptverfasser: Yung, Bryan S., Brand, Cameron S., Xiang, Sunny Y., Gray, Charles B. B., Means, Christopher K., Rosen, Hugh, Chun, Jerold, Purcell, Nicole, Brown, Joan Heller, Miyamoto, Shigeki
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410967/
https://ncbi.nlm.nih.gov/pubmed/28017639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.12.008
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