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Selective Coupling of the S1P(3) Receptor Subtype to S1P-mediated RhoA Activation and Cardioprotection

Sphingosine-1-phosphate (S1P), a bioactive lysophospholipid, is generated and released at sites of tissue injury in the heart and can act on S1P(1), S1P(2), and S1P(3) receptor subtypes to affect cardiovascular responses. We established that S1P causes little phosphoinositide hydrolysis and does not...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Yung, Bryan S., Brand, Cameron S., Xiang, Sunny Y., Gray, Charles B. B., Means, Christopher K., Rosen, Hugh, Chun, Jerold, Purcell, Nicole, Brown, Joan Heller, Miyamoto, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410967/
https://ncbi.nlm.nih.gov/pubmed/28017639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.12.008
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