Selective Coupling of the S1P(3) Receptor Subtype to S1P-mediated RhoA Activation and Cardioprotection

Sphingosine-1-phosphate (S1P), a bioactive lysophospholipid, is generated and released at sites of tissue injury in the heart and can act on S1P(1), S1P(2), and S1P(3) receptor subtypes to affect cardiovascular responses. We established that S1P causes little phosphoinositide hydrolysis and does not...

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Pubblicato in:J Mol Cell Cardiol
Autori principali: Yung, Bryan S., Brand, Cameron S., Xiang, Sunny Y., Gray, Charles B. B., Means, Christopher K., Rosen, Hugh, Chun, Jerold, Purcell, Nicole, Brown, Joan Heller, Miyamoto, Shigeki
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410967/
https://ncbi.nlm.nih.gov/pubmed/28017639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.12.008
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