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PLCε, PKD1, and SSH1L Transduce RhoA Signaling to Protect Mitochondria from Oxidative Stress in the Heart
Activation of the small guanosine triphosphatase (GTPase) RhoA can promote cell survival in cultured cardiomyocytes and in the heart. Here, we showed that the circulating lysophospholipid sphingosine 1-phosphate (S1P), a G-protein coupled receptor agonist, signaled through RhoA and phospholipase C ε...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035240/ https://ncbi.nlm.nih.gov/pubmed/24345679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004405 |
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