Selective targeting of the stress chaperome as a therapeutic strategy

Por Taldone, Tony, Ochiana, Stefan O., Patel, Pallav D., Chiosis, Gabriela
Publicado no Trends Pharmacol Sci (2014)

Hydrochlorothiazide vs Venlafaxine: Drug-induced Bullous Pemphigoid

Por Naramala, Srikanth, Dalal, Hussain, Adapa, Sreedhar, Patel, Pallav, Konala, Venu Madhav
Publicado no Cureus (2019)

An Unusual Presentation From a Sporadic Partially Acid-Fast Aerobic Actinomycete Resistant to Common Antibiotics

Por Adapa, Sreedhar, Naramala, Srikanth, Gayam, Vijay, Kapoor, Rajan, Raju, Mina, Patel, Pallav, Konala, Venu Madhav
Publicado no J Investig Med High Impact Case Rep (2020)

Calciphylaxis in a Patient on Home Hemodialysis

Por Adapa, Sreedhar, Naramala, Srikanth, Gayam, Vijay, Koduri, Narayana Murty, Daggubati, Subba Rao, Patel, Pallav, Konala, Venu Madhav
Publicado no J Investig Med High Impact Case Rep (2020)

Assay Strategies for the Discovery and Validation of Therapeutics Targeting Brugia pahangi Hsp90

Por Taldone, Tony, Gillan, Victoria, Sun, Weilin, Rodina, Anna, Patel, Pallav, Maitland, Kirsty, O'Neill, Kerry, Chiosis, Gabriela, Devaney, Eileen
Publicado em 2010

Design, Synthesis and Evaluation of Small Molecule Hsp90 Probes

Por Taldone, Tony, Zatorska, Danuta, Patel, Pallav D., Zong, Hongliang, Rodina, Anna, Ahn, James H., Moulick, Kamalika, Guzman, Monica L., Chiosis, Gabriela
Publicado em 2011

Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series

Por Taldone, Tony, Patel, Pallav D., Patel, Maulik, Patel, Hardik J., Evans, Christopher E., Rodina, Anna, Ochiana, Stefan, Shah, Smit K., Uddin, Mohammad, Gewirth, Daniel, Chiosis, Gabriela
Publicado em 2013

Paralog-selective Hsp90 inhibitors define tumor-specific regulation of Her2

Por Patel, Pallav D., Yan, Pengrong, Seidler, Paul M., Patel, Hardik J., Sun, Weilin, Yang, Chenghua, Que, Nanette S., Taldone, Tony, Finotti, Paola, Stephani, Ralph A., Gewirth, Daniel T., Chiosis, Gabriela
Publicado em 2013

Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5-(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70

Por Kang, Yanlong, Taldone, Tony, Patel, Hardik J., Patel, Pallav D., Rodina, Anna, Gozman, Alexander, Maharaj, Ronnie, Clement, Cristina C., Patel, Maulik R., Brodsky, Jeffrey L., Young, Jason C., Chiosis, Gabriela
Publicado em 2014

Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5-(Phenylthio)pyrimidines, 2-(Pyridin-3-ylthio)pyrimidines, and 3-(Phenylthio)pyridines as Reversible Binders to an All...

Por Taldone, Tony, Kang, Yanlong, Patel, Hardik J., Patel, Maulik R., Patel, Pallav D., Rodina, Anna, Patel, Yogita, Gozman, Alexander, Maharaj, Ronnie, Clement, Cristina C., Lu, Alvin, Young, Jason C., Chiosis, Gabriela
Publicado em 2014

Structure–Activity Relationship in a Purine-Scaffold Compound Series with Selectivity for the Endoplasmic Reticulum Hsp90 Paralog Grp94

Por Patel, Hardik J., Patel, Pallav D., Ochiana, Stefan O., Yan, Pengrong, Sun, Weilin, Patel, Maulik R., Shah, Smit K., Tramentozzi, Elisa, Brooks, James, Bolaender, Alexander, Shrestha, Liza, Stephani, Ralph, Finotti, Paola, Leifer, Cynthia, Li, Zihai, Gewirth, Daniel T., Taldone, Tony, Chiosis, Gabriela
Publicado no J Med Chem (2015)

Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein

Por Rodina, Anna, Patel, Pallav D., Kang, Yanlong, Patel, Yogita, Baaklini, Imad, Wong, Michael J.H., Taldone, Tony, Yan, Pengrong, Yang, Chenghua, Maharaj, Ronnie, Gozman, Alexander, Patel, Maulik R., Patel, Hardik J., Chirico, William, Erdjument-Bromage, Hediye, Talele, Tanaji T., Young, Jason C., Chiosis, Gabriela
Publicado em 2013

Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer

Por Rodina, Anna, Taldone, Tony, Kang, Yanlong, Patel, Pallav D., Koren, John, Yan, Pengrong, DaGama Gomes, Erica M., Yang, Chenghua, Patel, Maulik R., Shrestha, Liza, Ochiana, Stefan O., Santarossa, Cristina, Maharaj, Ronnie, Gozman, Alexander, Cox, Marc B., Erdjument-Bromage, Hediye, Hendrickson, Ronald C., Cerchietti, Leandro, Melnick, Ari, Guzman, Monica L., Chiosis, Gabriela
Publicado em 2014