The Relationship of Photoreceptor Degeneration to Retinal Vascular Development and Loss in Mutant Rhodopsin Transgenic and RCS Rats

Por Pennesi, Mark E., Nishikawa, Shimpei, Matthes, Michael T., Yasumura, Douglas, LaVail, Matthew M.
Publicado em 2008

Suppression of rds Expression by siRNA and Gene Replacement Strategies for Gene Therapy Using rAAV Vector

Por Petrs-Silva, Hilda, Yasumura, Douglas, Matthes, Michael T., LaVail, Matthew M., Lewin, Alfred S., Hauswirth, William W.
Publicado em 2012

Gene Therapy for MERTK-Associated Retinal Degenerations

Por LaVail, Matthew M., Yasumura, Douglas, Matthes, Michael T., Yang, Haidong, Hauswirth, William W., Deng, Wen-Tao, Vollrath, Douglas
Publicado no Adv Exp Med Biol (2016)

Ribozyme rescue of photoreceptor cells in P23H transgenic rats: Long-term survival and late-stage therapy

Por LaVail, Matthew M., Yasumura, Douglas, Matthes, Michael T., Drenser, Kimberly A., Flannery, John G., Lewin, Alfred S., Hauswirth, William W.
Publicado em 2000

Regulation and Prognostic Relevance of Symmetric Dimethylarginine Serum Concentrations in Critical Illness and Sepsis

Por Koch, Alexander, Weiskirchen, Ralf, Bruensing, Jan, Dückers, Hanna, Buendgens, Lukas, Kunze, Julian, Matthes, Michael, Luedde, Tom, Trautwein, Christian, Tacke, Frank
Publicado em 2013

Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin

Por Chiang, Wei-Chieh, Joseph, Victory, Yasumura, Douglas, Matthes, Michael T., Lewin, Alfred S., Gorbatyuk, Marina S., Ahern, Kelly, LaVail, Matthew M., Lin, Jonathan H.
Publicado no Adv Exp Med Biol (2016)

Tyro3 Modulates Mertk-Associated Retinal Degeneration

Por Vollrath, Douglas, Yasumura, Douglas, Benchorin, Gillie, Matthes, Michael T., Feng, Wei, Nguyen, Natalie M., Sedano, Cecilia D., Calton, Melissa A., LaVail, Matthew M.
Publicado no PLoS Genet (2015)

Correction of the retinal dystrophy phenotype of the RCS rat by viral gene transfer of Mertk

Por Vollrath, Douglas, Feng, Wei, Duncan, Jacque L., Yasumura, Douglas, D'Cruz, Patricia M., Chappelow, Aimee, Matthes, Michael T., Kay, Mark A., LaVail, Matthew M.
Publicado em 2001

In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse

Por Alavi, Marcel V., Chiang, Wei-Chieh, Kroeger, Heike, Yasumura, Douglas, Matthes, Michael T., Iwawaki, Takao, LaVail, Matthew M., Gould, Douglas B., Lin, Jonathan H.
Publicado no Invest Ophthalmol Vis Sci (2015)

Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration

Por Chiang, Wei-Chieh, Kroeger, Heike, Sakami, Sanae, Messah, Carissa, Yasumura, Douglas, Matthes, Michael T., Coppinger, Judith A., Palczewski, Krzysztof, LaVail, Matthew M., Lin, Jonathan H.
Publicado no Mol Neurobiol (2014)

Sustained Delivery of NT-3 from Lens Fiber Cells in Transgenic Mice Reveals Specificity of Neuroprotection in Retinal Degenerations

Por LaVail, Matthew M., Nishikawa, Shimpei, Duncan, Jacque L., Yang, Haidong, Matthes, Michael T., Yasumura, Douglas, Vollrath, Douglas, Overbeek, Paul A., Ash, John D., Robinson, Michael L.
Publicado em 2008

Induction of Endoplasmic Reticulum Stress Genes, BiP and Chop, in Genetic and Environmental Models of Retinal Degeneration

Por Kroeger, Heike, Messah, Carissa, Ahern, Kelly, Gee, Jason, Joseph, Victory, Matthes, Michael T., Yasumura, Douglas, Gorbatyuk, Marina S., Chiang, Wei-Chieh, LaVail, Matthew M., Lin, Jonathan H.
Publicado em 2012

Intravitreal Administration of HA-1077, a ROCK Inhibitor, Improves Retinal Function in a Mouse Model of Huntington Disease

Por Li, Mei, Yasumura, Douglas, Ma, Aye Aye K., Matthes, Michael T., Yang, Haidong, Nielson, Gregory, Huang, Yong, Szoka, Francis C., LaVail, Matthew M., Diamond, Marc I.
Publicado em 2013

Sphingolipid profile alters in retinal dystrophic P23H-1 rats and systemic FTY720 can delay retinal degeneration

Por Stiles, Megan, Qi, Hui, Sun, Eleanor, Tan, Jeremy, Porter, Hunter, Allegood, Jeremy, Chalfant, Charles E., Yasumura, Douglas, Matthes, Michael T., LaVail, Matthew M., Mandal, Nawajes A.
Publicado no J Lipid Res (2016)

mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice

Por Zhao, Chen, Yasumura, Douglas, Li, Xiyan, Matthes, Michael, Lloyd, Marcia, Nielsen, Gregory, Ahern, Kelly, Snyder, Michael, Bok, Dean, Dunaief, Joshua L., LaVail, Matthew M., Vollrath, Douglas
Publicado em 2010

Ceramide Signaling in Retinal Degeneration

Por Chen, Hui, Tran, Julie-Thu A., Brush, Richard S., Saadi, Anisse, Rahman, Abul K., Yu, Man, Yasumura, Douglas, Matthes, Michael T., Ahern, Kelly, Yang, Haidong, LaVail, Matthew M., Mandal, Md Nawajes A.
Publicado em 2012

Discordant Anatomical, Electrophysiological, and Visual Behavioral Profiles of Retinal Degeneration in Rat Models of Retinal Degenerative Disease

Por McGill, Trevor J., Prusky, Glen T., Douglas, Robert M., Yasumura, Douglas, Matthes, Michael T., Lowe, Robert J., Duncan, Jacque L., Yang, Haidong, Ahern, Kelly, Daniello, Kate M., Silver, Byron, LaVail, Matthew M.
Publicado em 2012

Allele-Specific Inhibition of Rhodopsin With an Antisense Oligonucleotide Slows Photoreceptor Cell Degeneration

Por Murray, Susan F., Jazayeri, Ali, Matthes, Michael T., Yasumura, Douglas, Yang, Haidong, Peralta, Raechel, Watt, Andy, Freier, Sue, Hung, Gene, Adamson, Peter S., Guo, Shuling, Monia, Brett P., LaVail, Matthew M., McCaleb, Michael L.
Publicado no Invest Ophthalmol Vis Sci (2015)

Stanniocalcin-1 Rescued Photoreceptor Degeneration in Two Rat Models of Inherited Retinal Degeneration

Por Roddy, Gavin W, Rosa Jr, Robert H, Youn Oh, Joo, Ylostalo, Joni H, Bartosh, Thomas J, Choi, Hosoon, Lee, Ryang Hwa, Yasumura, Douglas, Ahern, Kelly, Nielsen, Gregory, Matthes, Michael T, LaVail, Matthew M, Prockop, Darwin J
Publicado em 2012

Tyrosine-Mutant AAV8 Delivery of Human MERTK Provides Long-Term Retinal Preservation in RCS Rats

Por Deng, Wen-Tao, Dinculescu, Astra, Li, Qiuhong, Boye, Sanford L., Li, Jie, Gorbatyuk, Marina S., Pang, Jijing, Chiodo, Vince A., Matthes, Michael T., Yasumura, Douglas, Liu, Li, Alkuraya, Fowzan S., Zhang, Kang, Vollrath, Douglas, LaVail, Matthew M., Hauswirth, William W.
Publicado em 2012