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Stanniocalcin-1 Rescued Photoreceptor Degeneration in Two Rat Models of Inherited Retinal Degeneration

Oxidative stress and photoreceptor apoptosis are prominent features of many forms of retinal degeneration (RD) for which there are currently no effective therapies. We previously observed that mesenchymal stem/stromal cells reduce apoptosis by being activated to secrete stanniocalcin-1 (STC-1), a mu...

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Bibliographic Details
Main Authors: Roddy, Gavin W, Rosa Jr, Robert H, Youn Oh, Joo, Ylostalo, Joni H, Bartosh, Thomas J, Choi, Hosoon, Lee, Ryang Hwa, Yasumura, Douglas, Ahern, Kelly, Nielsen, Gregory, Matthes, Michael T, LaVail, Matthew M, Prockop, Darwin J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321604/
https://ncbi.nlm.nih.gov/pubmed/22294148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.308
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