Dual Adeno-Associated Virus Vectors Result in Efficient In Vitro and In Vivo Expression of an Oversized Gene, MYO7A

Por Dyka, Frank M., Boye, Sanford L., Chiodo, Vince A., Hauswirth, William W., Boye, Shannon E.
Publicado em 2014

Whirlin Replacement Restores the Formation of the USH2 Protein Complex in Whirlin Knockout Photoreceptors

Por Zou, Junhuang, Luo, Ling, Shen, Zuolian, Chiodo, Vince A., Ambati, Balamurali K., Hauswirth, William W., Yang, Jun
Publicado em 2011

Inhibitor of Apoptosis-Stimulating Protein of p53 (iASPP) Is Required for Neuronal Survival after Axonal Injury

Por Wilson, Ariel M., Chiodo, Vince A., Boye, Sanford L., Brecha, Nicholas C., Hauswirth, William W., Di Polo, Adriana
Publicado em 2014

Cone Specific Promoter for Use in Gene Therapy of Retinal Degenerative Diseases

Por Dyka, Frank M., Boye, Sanford L., Ryals, Renee C., Chiodo, Vince A., Boye, Shannon E., Hauswirth, William W.
Publicado no Adv Exp Med Biol (2014)

rAAV2/5 gene-targeting to rods: dose-dependent efficiency and complications associated with different promoters

Por Beltran, William A., Boye, Sanford L., Boye, Shannon E., Chiodo, Vince A., Lewin, Alfred S., Hauswirth, William W., Aguirre, Gustavo D.
Publicado em 2010

Gene therapy using self-complementary Y733F capsid mutant AAV2/8 restores vision in a model of early onset Leber congenital amaurosis

Por Ku, Cristy A., Chiodo, Vince A., Boye, Sanford L., Goldberg, Andrew F.X., Li, Tiansen, Hauswirth, William W., Ramamurthy, Visvanathan
Publicado em 2011

Viral-mediated vision rescue of a novel AIPL1 cone-rod dystrophy model

Por Ku, Cristy A., Chiodo, Vince A., Boye, Sanford L., Hayes, Abigail, Goldberg, Andrew F.X., Hauswirth, William W., Ramamurthy, Visvanathan
Publicado no Hum Mol Genet (2015)

Occludin S490 Phosphorylation Regulates Vascular Endothelial Growth Factor–Induced Retinal Neovascularization

Por Liu, Xuwen, Dreffs, Alyssa, Díaz-Coránguez, Monica, Runkle, E. Aaron, Gardner, Thomas W., Chiodo, Vince A., Hauswirth, William W., Antonetti, David A.
Publicado no Am J Pathol (2016)

ER Stress Is Involved in T17M Rhodopsin-Induced Retinal Degeneration

Por Kunte, Mansi M., Choudhury, Shreyasi, Manheim, Jessica F., Shinde, Vishal M., Miura, Masayuki, Chiodo, Vince A., Hauswirth, William W., Gorbatyuk, Oleg S., Gorbatyuk, Marina S.
Publicado em 2012

In vivo knockdown of Piccolino disrupts presynaptic ribbon morphology in mouse photoreceptor synapses

Por Regus-Leidig, Hanna, Fuchs, Michaela, Löhner, Martina, Leist, Sarah R., Leal-Ortiz, Sergio, Chiodo, Vince A., Hauswirth, William W., Garner, Craig C., Brandstätter, Johann H.
Publicado em 2014

Imaging the response of the retina to electrical stimulation with genetically encoded calcium indicators

Por Weitz, Andrew C., Behrend, Matthew R., Lee, Nan Sook, Klein, Ronald L., Chiodo, Vince A., Hauswirth, William W., Humayun, Mark S., Weiland, James D., Chow, Robert H.
Publicado em 2013

RD3 gene delivery restores guanylate cyclase localization and rescues photoreceptors in the Rd3 mouse model of Leber congenital amaurosis 12

Por Molday, Laurie L., Djajadi, Hidayat, Yan, Paul, Szczygiel, Lukasz, Boye, Sanford L., Chiodo, Vince A., Gregory-Evans, Kevin, Sarunic, Marinko V., Hauswirth, William W., Molday, Robert S.
Publicado em 2013

AAV8(Y733F)-mediated gene therapy in a Spata7 knockout mouse model of Leber congenital amaurosis and retinitis pigmentosa

Por Zhong, Hua, Eblimit, Aiden, Moayedi, Yalda, Boye, Sanford L, Chiodo, Vince A, Chen, Yiyun, Li, Yumei, Nichols, Ralph M, Hauswirth, William W, Chen, Rui, Mardon, Graeme
Publicado no Gene Ther (2015)

Organizational motifs for ground squirrel cone bipolar cells

Por Light, Adam C., Zhu, Yongling, Shi, Jun, Saszik, Shannon, Lindstrom, Sarah, Davidson, Laura, Li, Xiaoyu, Chiodo, Vince A., Hauswirth, William W., Li, Wei, DeVries, Steven H.
Publicado em 2012

Gene therapy rescues cone function in congenital achromatopsia

Por Komáromy, András M., Alexander, John J., Rowlan, Jessica S., Garcia, Monique M., Chiodo, Vince A., Kaya, Asli, Tanaka, Jacqueline C., Acland, Gregory M., Hauswirth, William W., Aguirre, Gustavo D.
Publicado em 2010

Gene therapy rescues cone function in congenital achromatopsia

Por Komáromy, András M., Alexander, John J., Rowlan, Jessica S., Garcia, Monique M., Chiodo, Vince A., Kaya, Asli, Tanaka, Jacqueline C., Acland, Gregory M., Hauswirth, William W., Aguirre, Gustavo D.
Publicado em 2011

Stability and Safety of an AAV Vector for Treating RPGR-ORF15 X-Linked Retinitis Pigmentosa

Por Deng, Wen-Tao, Dyka, Frank M., Dinculescu, Astra, Li, Jie, Zhu, Ping, Chiodo, Vince A., Boye, Sanford L., Conlon, Thomas J., Erger, Kirsten, Cossette, Travis, Hauswirth, William W.
Publicado no Hum Gene Ther (2015)

Consequences of zygote injection and germline transfer of mutant human mitochondrial DNA in mice

Por Yu, Hong, Koilkonda, Rajeshwari D., Chou, Tsung-Han, Porciatti, Vittorio, Mehta, Arpit, Hentall, Ian D., Chiodo, Vince A., Boye, Sanford L., Hauswirth, William W., Lewin, Alfred S., Guy, John
Publicado no Proc Natl Acad Sci U S A (2015)

Functional interchangeability of rod and cone transducin α-subunits

Por Deng, Wen-Tao, Sakurai, Keisuke, Liu, Jianwen, Dinculescu, Astra, Li, Jie, Pang, Jijing, Min, Seok-Hong, Chiodo, Vince A., Boye, Sanford L., Chang, Bo, Kefalov, Vladimir J., Hauswirth, William W.
Publicado em 2009

Cone Phosphodiesterase-6α′ Restores Rod Function and Confers Distinct Physiological Properties in the Rod Phosphodiesterase-6β-Deficient rd10 Mouse

Por Deng, Wen-Tao, Sakurai, Keisuke, Kolandaivelu, Saravanan, Kolesnikov, Alexander V., Dinculescu, Astra, Li, Jie, Zhu, Ping, Liu, Xuan, Pang, Jijing, Chiodo, Vince A., Boye, Sanford L., Chang, Bo, Ramamurthy, Visvanathan, Kefalov, Vladimir J., Hauswirth, William W.
Publicado em 2013