Dual ABCA4-AAV Vector Treatment Reduces Pathogenic Retinal A2E Accumulation in a Mouse Model of Autosomal Recessive Stargardt Disease

by Dyka, Frank M., Molday, Laurie L., Chiodo, Vince A., Molday, Robert S., Hauswirth, William W.
Published in Hum Gene Ther (2019)

Dual Adeno-Associated Virus Vectors Result in Efficient In Vitro and In Vivo Expression of an Oversized Gene, MYO7A

by Dyka, Frank M., Boye, Sanford L., Chiodo, Vince A., Hauswirth, William W., Boye, Shannon E.
Published 2014

Characterization and Purification of the Discoidin Domain Containing Protein Retinoschisin (RS1) and Its Interaction with Galactose

by Dyka, Frank M., Wu, Winco W.H., Pfeifer, Tom A., Molday, Laurie L., Grigliatti, Thomas A., Molday, Robert S.
Published 2008

Cone Specific Promoter for Use in Gene Therapy of Retinal Degenerative Diseases

by Dyka, Frank M., Boye, Sanford L., Ryals, Renee C., Chiodo, Vince A., Boye, Shannon E., Hauswirth, William W.
Published in Adv Exp Med Biol (2014)

Relation of Response to Treatment with Dorzolamide in X-linked Retinoschisis to the Mechanism of Functional Loss in Retinoschisin

by Walia, Saloni, Fishman, Gerald A., Molday, Robert S., Dyka, Frank M., Kumar, Nalin M., Ehlinger, Mary A., Stone, Edwin M.
Published 2008

Pathological Effects of Mutant C1QTNF5 (S163R) Expression in Murine Retinal Pigment Epithelium

by Dinculescu, Astra, Min, Seok-Hong, Dyka, Frank M., Deng, Wen-Tao, Stupay, Rachel M., Chiodo, Vince, Smith, W. Clay, Hauswirth, William W.
Published in Invest Ophthalmol Vis Sci (2015)

Long-term Preservation of Cone Photoreceptors and Restoration of Cone Function by Gene Therapy in the Guanylate Cyclase-1 Knockout (GC1KO) Mouse

by Boye, Sanford L., Conlon, Thomas, Erger, Kirsten, Ryals, Renee, Neeley, Andy, Cossette, Travis, Pang, Jijing, Dyka, Frank M., Hauswirth, William W., Boye, Shannon E.
Published 2011

Stability and Safety of an AAV Vector for Treating RPGR-ORF15 X-Linked Retinitis Pigmentosa

by Deng, Wen-Tao, Dyka, Frank M., Dinculescu, Astra, Li, Jie, Zhu, Ping, Chiodo, Vince A., Boye, Sanford L., Conlon, Thomas J., Erger, Kirsten, Cossette, Travis, Hauswirth, William W.
Published in Hum Gene Ther (2015)

Clarin‐1 expression in adult mouse and human retina highlights a role of Müller glia in Usher syndrome

by Xu, Lei, Bolch, Susan N, Santiago, Clayton P, Dyka, Frank M, Akil, Omar, Lobanova, Ekaterina S, Wang, Yuchen, Martemyanov, Kirill A, Hauswirth, William W, Smith, W Clay, Handa, James T, Blackshaw, Seth, Ash, John D, Dinculescu, Astra
Published in J Pathol (2019)

Targeting Photoreceptors via Intravitreal Delivery Using Novel, Capsid-Mutated AAV Vectors

by Kay, Christine N., Ryals, Renee C., Aslanidi, George V., Min, Seok Hong, Ruan, Qing, Sun, Jingfen, Dyka, Frank M., Kasuga, Daniel, Ayala, Andrea E., Van Vliet, Kim, Agbandje-McKenna, Mavis, Hauswirth, William W., Boye, Sanford L., Boye, Shannon E.
Published 2013

Correction: Targeting Photoreceptors via Intravitreal Delivery Using Novel, Capsid-Mutated AAV Vectors

by Kay, Christine N., Ryals, Renee C., Aslanidi, George V., Min, Seok Hong, Ruan, Qing, Sun, Jingfen, Dyka, Frank M., Kasuga, Daniel, Ayala, Andrea E., Van Vliet, Kim, Agbandje-McKenna, Mavis, Hauswirth, William W., Boye, Sanford L., Boye, Shannon E.
Published 2013

Intravitreal delivery of a novel AAV vector targets ON bipolar cells and restores visual function in a mouse model of complete congenital stationary night blindness

by Scalabrino, Miranda L., Boye, Sanford L., Fransen, Kathryn M. H., Noel, Jennifer M., Dyka, Frank M., Min, Seok Hong, Ruan, Qing, De Leeuw, Charles N., Simpson, Elizabeth M., Gregg, Ronald G., McCall, Maureen A., Peachey, Neal S., Boye, Shannon E.
Published in Hum Mol Genet (2015)

AAV-Mediated Gene Therapy in the Guanylate Cyclase (RetGC1/RetGC2) Double Knockout Mouse Model of Leber Congenital Amaurosis

by Boye, Sanford L., Peshenko, Igor V., Huang, Wei Chieh, Min, Seok Hong, McDoom, Issam, Kay, Christine N., Liu, Xuan, Dyka, Frank M., Foster, Thomas C., Umino, Yumiko, Karan, Sukanya, Jacobson, Samuel G., Baehr, Wolfgang, Dizhoor, Alexander, Hauswirth, William W., Boye, Shannon E.
Published 2013

AAV-Mediated Clarin-1 Expression in the Mouse Retina: Implications for USH3A Gene Therapy

by Dinculescu, Astra, Stupay, Rachel M., Deng, Wen-Tao, Dyka, Frank M., Min, Seok-Hong, Boye, Sanford L., Chiodo, Vince A., Abrahan, Carolina E., Zhu, Ping, Li, Qiuhong, Strettoi, Enrica, Novelli, Elena, Nagel-Wolfrum, Kerstin, Wolfrum, Uwe, Smith, W. Clay, Hauswirth, William W.
Published in PLoS One (2016)

Targeted CNS delivery using human MiniPromoters and demonstrated compatibility with adeno-associated viral vectors

by de Leeuw, Charles N, Dyka, Frank M, Boye, Sanford L, Laprise, Stéphanie, Zhou, Michelle, Chou, Alice Y, Borretta, Lisa, McInerny, Simone C, Banks, Kathleen G, Portales-Casamar, Elodie, Swanson, Magdalena I, D’Souza, Cletus A, Boye, Shannon E, Jones, Steven JM, Holt, Robert A, Goldowitz, Daniel, Hauswirth, William W, Wasserman, Wyeth W, Simpson, Elizabeth M
Published 2014