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Cone Specific Promoter for Use in Gene Therapy of Retinal Degenerative Diseases

Achromatopsia (ACHM) is caused by a progressive loss of cone photoreceptors leading to color blindness and poor visual acuity. Animal studies and human clinical trials have shown that gene replacement therapy with adeno-associate virus (AAV) is a viable treatment option for this disease. Although th...

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Dades bibliogràfiques
Publicat a:Adv Exp Med Biol
Autors principals: Dyka, Frank M., Boye, Sanford L., Ryals, Renee C., Chiodo, Vince A., Boye, Shannon E., Hauswirth, William W.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450355/
https://ncbi.nlm.nih.gov/pubmed/24664760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-3209-8_87
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