AAV-Mediated Gene Therapy in the Guanylate Cyclase (RetGC1/RetGC2) Double Knockout Mouse Model of Leber Congenital Amaurosis

Mutations in GUCY2D are associated with recessive Leber congenital amaurosis-1 (LCA1). GUCY2D encodes photoreceptor-specific, retinal guanylate cyclase-1 (RetGC1). Reports of retinal degeneration in LCA1 are conflicting; some describe no obvious degeneration and others report loss of both rods and c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Boye, Sanford L., Peshenko, Igor V., Huang, Wei Chieh, Min, Seok Hong, McDoom, Issam, Kay, Christine N., Liu, Xuan, Dyka, Frank M., Foster, Thomas C., Umino, Yumiko, Karan, Sukanya, Jacobson, Samuel G., Baehr, Wolfgang, Dizhoor, Alexander, Hauswirth, William W., Boye, Shannon E.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581260/
https://ncbi.nlm.nih.gov/pubmed/23210611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.193
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados