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Evaluating the Role of Retinal Membrane Guanylyl Cyclase 1 (RetGC1) Domains in Binding Guanylyl Cyclase-activating Proteins (GCAPs)

Retinal membrane guanylyl cyclase 1 (RetGC1) regulated by guanylyl cyclase-activating proteins (GCAPs) controls photoreceptor recovery and when mutated causes blinding disorders. We evaluated the principal models of how GCAP1 and GCAP2 bind RetGC1: through a shared docking interface versus independe...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Peshenko, Igor V., Olshevskaya, Elena V., Dizhoor, Alexander M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358116/
https://ncbi.nlm.nih.gov/pubmed/25616661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.629642
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