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Binding of Guanylyl Cyclase Activating Protein 1 (GCAP1) to Retinal Guanylyl Cyclase (RetGC1): THE ROLE OF INDIVIDUAL EF-HANDS

Guanylyl cyclase activating protein 1 (GCAP1), after substitution of Ca(2+) by Mg(2+) in its EF-hands, stimulates photoreceptor guanylyl cyclase, RetGC1, in response to light. We inactivated metal binding in individual EF-hands of GCAP1 tagged with green fluorescent protein to assess their role in G...

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Bibliographische Detailangaben
Hauptverfasser: Peshenko, Igor V., Olshevskaya, Elena V., Dizhoor, Alexander M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490776/
https://ncbi.nlm.nih.gov/pubmed/18541533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801899200
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