Activation of Retinal Guanylyl Cyclase RetGC1 by GCAP1: Stoichiometry of Binding and the Effect of New LCA-Related Mutations

Retinal membrane guanylyl cyclase (retGC) and Ca(2+)/Mg(2+) -sensor proteins, GCAPs(1), control the recovery of the photoresponse in vertebrate photoreceptors, through their molecular interactions that remain rather poorly understood and controversial. Here we have determined the main retGC isozyme...

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Hlavní autoři: Peshenko, Igor V., Olshevskaya, Elena V., Yao, Suxia, Ezzeldin, Hany H., Pittler, Steven J., Dizhoor, Alexander M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827208/
https://ncbi.nlm.nih.gov/pubmed/20050595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901495y
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