Enzymatic properties and regulation of the native isozymes of retinal membrane guanylyl cyclase (RetGC) from mouse photoreceptors

Mouse photoreceptor function and survival critically depend on Ca(2+)-regulated retinal membrane guanylyl cyclase (RetGC), comprised of two isozymes, RetGC1 and RetGC2. We characterized the content, catalytic constants and regulation of native RetGC1 and RetGC2 isozymes using mice lacking guanylyl c...

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Main Authors: Peshenko, Igor V., Olshevskaya, Elena V., Savchenko, Andrey B., Karan, Sukanya, Palczewski, Krzysztof, Baehr, Wolfgang, Dizhoor, Alexander M.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127287/
https://ncbi.nlm.nih.gov/pubmed/21598940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200491b
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