ロード中...
The R838S Mutation in Retinal Guanylyl Cyclase 1 (RetGC1) Alters Calcium Sensitivity of cGMP Synthesis in the Retina and Causes Blindness in Transgenic Mice
Substitutions of Arg(838) in the dimerization domain of a human retinal membrane guanylyl cyclase 1 (RetGC1) linked to autosomal dominant cone-rod degeneration type 6 (CORD6) change RetGC1 regulation in vitro by Ca(2+). In addition, we find that R838S substitution makes RetGC1 less sensitive to inhi...
保存先:
| 出版年: | J Biol Chem |
|---|---|
| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2016
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114404/ https://ncbi.nlm.nih.gov/pubmed/27703005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.755553 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|