Llwytho...

Identification of Target Binding Site in Photoreceptor Guanylyl Cyclase-activating Protein 1 (GCAP1)

Retinal guanylyl cyclase (RetGC)-activating proteins (GCAPs) regulate visual photoresponse and trigger congenital retinal diseases in humans, but GCAP interaction with its target enzyme remains obscure. We mapped GCAP1 residues comprising the RetGC1 binding site by mutagenizing the entire surface of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Peshenko, Igor V., Olshevskaya, Elena V., Lim, Sunghyuk, Ames, James B., Dizhoor, Alexander M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974984/
https://ncbi.nlm.nih.gov/pubmed/24567338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.540716
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