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Structure of Guanylyl Cyclase Activator Protein 1 (GCAP1) Mutant V77E in a Ca(2+)-free/Mg(2+)-bound Activator State

GCAP1, a member of the neuronal calcium sensor subclass of the calmodulin superfamily, confers Ca(2+)-sensitive activation of retinal guanylyl cyclase 1 (RetGC1). We present NMR resonance assignments, residual dipolar coupling data, functional analysis, and a structural model of GCAP1 mutant (GCAP1(...

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書誌詳細
出版年:J Biol Chem
主要な著者: Lim, Sunghyuk, Peshenko, Igor V., Olshevskaya, Elena V., Dizhoor, Alexander M., Ames, James B.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813471/
https://ncbi.nlm.nih.gov/pubmed/26703466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.696161
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