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Structure of Guanylyl Cyclase Activator Protein 1 (GCAP1) Mutant V77E in a Ca(2+)-free/Mg(2+)-bound Activator State
GCAP1, a member of the neuronal calcium sensor subclass of the calmodulin superfamily, confers Ca(2+)-sensitive activation of retinal guanylyl cyclase 1 (RetGC1). We present NMR resonance assignments, residual dipolar coupling data, functional analysis, and a structural model of GCAP1 mutant (GCAP1(...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813471/ https://ncbi.nlm.nih.gov/pubmed/26703466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.696161 |
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