Rescue of M-cone Function in Aged Opn1mw(−/−) Mice, a Model for Late-Stage Blue Cone Monochromacy

Autor Deng, Wen-Tao, Li, Jie, Zhu, Ping, Freedman, Beau, Smith, W. Clay, Baehr, Wolfgang, Hauswirth, William W.
Vydáno v Invest Ophthalmol Vis Sci (2019)

Gene Therapy for MERTK-Associated Retinal Degenerations

Autor LaVail, Matthew M., Yasumura, Douglas, Matthes, Michael T., Yang, Haidong, Hauswirth, William W., Deng, Wen-Tao, Vollrath, Douglas
Vydáno v Adv Exp Med Biol (2016)

Cone Phosphodiesterase-6γ’ Subunit Augments Cone PDE6 Holoenzyme Assembly and Stability in a Mouse Model Lacking Both Rod and Cone PDE6 Catalytic Subunits

Autor Deng, Wen-Tao, Kolandaivelu, Saravanan, Dinculescu, Astra, Li, Jie, Zhu, Ping, Chiodo, Vince A., Ramamurthy, Visvanathan, Hauswirth, William W.
Vydáno v Front Mol Neurosci (2018)

Pathological Effects of Mutant C1QTNF5 (S163R) Expression in Murine Retinal Pigment Epithelium

Autor Dinculescu, Astra, Min, Seok-Hong, Dyka, Frank M., Deng, Wen-Tao, Stupay, Rachel M., Chiodo, Vince, Smith, W. Clay, Hauswirth, William W.
Vydáno v Invest Ophthalmol Vis Sci (2015)

Human L- and M-opsins restore M-cone function in a mouse model for human blue cone monochromacy

Autor Deng, Wen-Tao, Li, Jie, Zhu, Ping, Chiodo, Vince A., Smith, W. Clay, Freedman, Beau, Baehr, Wolfgang, Pang, Jijing, Hauswirth, William W.
Vydáno v Mol Vis (2018)

Mechanistic Basis for the Failure of Cone Transducin to Translocate: Why Cones Are Never Blinded by Light

Autor Lobanova, Ekaterina S., Herrmann, Rolf, Finkelstein, Stella, Reidel, Boris, Skiba, Nikolai P., Deng, Wen-Tao, Jo, Rebecca, Weiss, Ellen R., Hauswirth, William W., Arshavsky, Vadim Y.
Vydáno 2010

AAV-Mediated Lysophosphatidylcholine Acyltransferase 1 (Lpcat1) Gene Replacement Therapy Rescues Retinal Degeneration in rd11 Mice

Autor Dai, Xufeng, Han, Juanjuan, Qi, Yan, Zhang, Hua, Xiang, Lue, Lv, Jineng, Li, Jie, Deng, Wen-Tao, Chang, Bo, Hauswirth, William W., Pang, Ji-jing
Vydáno 2014

Stability and Safety of an AAV Vector for Treating RPGR-ORF15 X-Linked Retinitis Pigmentosa

Autor Deng, Wen-Tao, Dyka, Frank M., Dinculescu, Astra, Li, Jie, Zhu, Ping, Chiodo, Vince A., Boye, Sanford L., Conlon, Thomas J., Erger, Kirsten, Cossette, Travis, Hauswirth, William W.
Vydáno v Hum Gene Ther (2015)

Functional interchangeability of rod and cone transducin α-subunits

Autor Deng, Wen-Tao, Sakurai, Keisuke, Liu, Jianwen, Dinculescu, Astra, Li, Jie, Pang, Jijing, Min, Seok-Hong, Chiodo, Vince A., Boye, Sanford L., Chang, Bo, Kefalov, Vladimir J., Hauswirth, William W.
Vydáno 2009

Gene-based Therapy in a Mouse Model of Blue Cone Monochromacy

Autor Zhang, Yuxin, Deng, Wen-Tao, Du, Wei, Zhu, Ping, Li, Jie, Xu, Fan, Sun, Jingfen, Gerstner, Cecilia D., Baehr, Wolfgang, Boye, Sanford L., Zhao, Chen, Hauswirth, William W., Pang, Ji-jing
Vydáno v Sci Rep (2017)

Publisher Correction: Gene-based Therapy in a Mouse Model of Blue Cone Monochromacy

Autor Zhang, Yuxin, Deng, Wen-Tao, Du, Wei, Zhu, Ping, Li, Jie, Xu, Fan, Sun, Jingfen, Gerstner, Cecilia D., Baehr, Wolfgang, Boye, Sanford L., Zhao, Chen, Hauswirth, William W., Pang, Ji-jing
Vydáno v Sci Rep (2018)

Cone Phosphodiesterase-6α′ Restores Rod Function and Confers Distinct Physiological Properties in the Rod Phosphodiesterase-6β-Deficient rd10 Mouse

Autor Deng, Wen-Tao, Sakurai, Keisuke, Kolandaivelu, Saravanan, Kolesnikov, Alexander V., Dinculescu, Astra, Li, Jie, Zhu, Ping, Liu, Xuan, Pang, Jijing, Chiodo, Vince A., Boye, Sanford L., Chang, Bo, Ramamurthy, Visvanathan, Kefalov, Vladimir J., Hauswirth, William W.
Vydáno 2013

Tyrosine-Mutant AAV8 Delivery of Human MERTK Provides Long-Term Retinal Preservation in RCS Rats

Autor Deng, Wen-Tao, Dinculescu, Astra, Li, Qiuhong, Boye, Sanford L., Li, Jie, Gorbatyuk, Marina S., Pang, Jijing, Chiodo, Vince A., Matthes, Michael T., Yasumura, Douglas, Liu, Li, Alkuraya, Fowzan S., Zhang, Kang, Vollrath, Douglas, LaVail, Matthew M., Hauswirth, William W.
Vydáno 2012

AAV-Mediated Cone Rescue in a Naturally Occurring Mouse Model of CNGA3-Achromatopsia

Autor Pang, Ji-jing, Deng, Wen-Tao, Dai, Xufeng, Lei, Bo, Everhart, Drew, Umino, Yumiko, Li, Jie, Zhang, Keqing, Mao, Song, Boye, Sanford L., Liu, Li, Chiodo, Vince A., Liu, Xuan, Shi, Wei, Tao, Ye, Chang, Bo, Hauswirth, William W.
Vydáno 2012

Correction: AAV-Mediated Cone Rescue in a Naturally Occurring Mouse Model of CNGA3-Achromatopsia

Autor Pang, Ji-jing, Deng, Wen-Tao, Dai, Xufeng, Lei, Bo, Everhart, Drew, Umino, Yumiko, Li, Jie, Zhang, Keqing, Mao, Song, Boye, Sanford L., Liu, Li, Chiodo, Vince A., Liu, Xuan, Shi, Wei, Tao, Ye, Chang, Bo, Hauswirth, William W.
Vydáno 2014

Successful arrest of photoreceptor and vision loss expands the therapeutic window of retinal gene therapy to later stages of disease

Autor Beltran, William A., Cideciyan, Artur V., Iwabe, Simone, Swider, Malgorzata, Kosyk, Mychajlo S., McDaid, Kendra, Martynyuk, Inna, Ying, Gui-Shuang, Shaffer, James, Deng, Wen-Tao, Boye, Sanford L., Lewin, Alfred S., Hauswirth, William W., Jacobson, Samuel G., Aguirre, Gustavo D.
Vydáno v Proc Natl Acad Sci U S A (2015)

Vitreal delivery of AAV vectored Cnga3 restores cone function in CNGA3(−/−)/Nrl(−/−) mice, an all-cone model of CNGA3 achromatopsia(†)

Autor Du, Wei, Tao, Ye, Deng, Wen-Tao, Zhu, Ping, Li, Jie, Dai, Xufeng, Zhang, Yuxin, Shi, Wei, Liu, Xuan, Chiodo, Vince A., Ding, Xi-Qin, Zhao, Chen, Michalakis, Stylianos, Biel, Martin, Zhang, Zuoming, Qu, Jia, Hauswirth, William W., Pang, Ji-jing
Vydáno v Hum Mol Genet (2015)

Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina

Autor Petrs-Silva, Hilda, Dinculescu, Astra, Li, Qiuhong, Deng, Wen-Tao, Pang, Ji-jing, Min, Seok-Hong, Chiodo, Vince, Neeley, Andy W, Govindasamy, Lakshmanan, Bennett, Antonette, Agbandje-McKenna, Mavis, Zhong, Li, Li, Baozheng, Jayandharan, Giridhara R, Srivastava, Arun, Lewin, Alfred S, Hauswirth, William W
Vydáno 2011

Preclinical Potency and Safety Studies of an AAV2-Mediated Gene Therapy Vector for the Treatment of MERTK Associated Retinitis Pigmentosa

Autor Conlon, Thomas J., Deng, Wen-Tao, Erger, Kirsten, Cossette, Travis, Pang, Ji-jing, Ryals, Renee, Clément, Nathalie, Cleaver, Brian, McDoom, Issam, Boye, Shannon E., Peden, Marc C., Sherwood, Mark B., Abernathy, Corinne R., Alkuraya, Fowzan S., Boye, Sanford L., Hauswirth, William W.
Vydáno 2013

AAV-Mediated Clarin-1 Expression in the Mouse Retina: Implications for USH3A Gene Therapy

Autor Dinculescu, Astra, Stupay, Rachel M., Deng, Wen-Tao, Dyka, Frank M., Min, Seok-Hong, Boye, Sanford L., Chiodo, Vince A., Abrahan, Carolina E., Zhu, Ping, Li, Qiuhong, Strettoi, Enrica, Novelli, Elena, Nagel-Wolfrum, Kerstin, Wolfrum, Uwe, Smith, W. Clay, Hauswirth, William W.
Vydáno v PLoS One (2016)