Lanean...
Vitreal delivery of AAV vectored Cnga3 restores cone function in CNGA3(−/−)/Nrl(−/−) mice, an all-cone model of CNGA3 achromatopsia(†)
The CNGA3(−/−)/Nrl(−/−) mouse is a cone-dominant model with Cnga3 channel deficiency, which partially mimics the all cone foveal structure of human achromatopsia 2 with CNGA3 mutations. Although subretinal (SR) AAV vector administration can transfect retinal cells efficiently, the injection-induced...
Gorde:
| Argitaratua izan da: | Hum Mol Genet |
|---|---|
| Egile Nagusiak: | , , , , , , , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2015
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4459390/ https://ncbi.nlm.nih.gov/pubmed/25855802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv114 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|