The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3-Deficient Mouse Model of Achromatopsia

Mutations in the CNGA3 gene, which encodes the A subunit of the cyclic guanosine monophosphate (cGMP)-gated cation channel in cone photoreceptor outer segments, cause total colour blindness, also referred to as achromatopsia. Cones lacking this channel protein are non-functional, accumulate high lev...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Koch, Mirja, Scheel, Constanze, Ma, Hongwei, Yang, Fan, Stadlmeier, Michael, Glück, Andrea F., Murenu, Elisa, Traube, Franziska R., Carell, Thomas, Biel, Martin, Ding, Xi-Qin, Michalakis, Stylianos
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793084/
https://ncbi.nlm.nih.gov/pubmed/33374621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010052
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi