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Gene Therapy for MERTK-Associated Retinal Degenerations
MERTK-associated retinal degenerations are thought to have defects in phagocytosis of shed outer segment membranes by the retinal pigment epithelium (RPE), as do the rodent models of these diseases. We have subretinally injected an RPE-specific AAV2 vector, AAV2-VMD2-hMERTK, to determine whether thi...
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| Publicado no: | Adv Exp Med Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4942279/ https://ncbi.nlm.nih.gov/pubmed/26427450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-17121-0_65 |
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