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An ENU-Induced Mutation in the Mertk Gene (Mertk(nmf12)) Leads to a Slow Form of Retinal Degeneration

PURPOSE. To determine the basis and to characterize the phenotype of a chemically induced mutation in a mouse model of retinal degeneration. METHODS. Screening by indirect ophthalmoscopy identified a line of N-ethyl-N-nitrosourea (ENU) mutagenized mice demonstrating retinal patches. Longitudinal stu...

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Bibliografische gegevens
Hoofdauteurs: Maddox, Dennis M., Hicks, Wanda L., Vollrath, Douglas, LaVail, Matthew M., Naggert, Jürgen K., Nishina, Patsy M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Association for Research in Vision and Ophthalmology, Inc. 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175976/
https://ncbi.nlm.nih.gov/pubmed/21436282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-7077
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